
5-Aminovaleric acid
CAS No. 660-88-8
5-Aminovaleric acid ( —— )
产品货号. M19658 CAS No. 660-88-8
5-氨基戊酸(或5-氨基戊酸)是赖氨酸降解产物。它可以内源产生,也可以通过赖氨酸的细菌分解代谢产生。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥502 | 有现货 |
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1G | ¥705 | 有现货 |
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生物学信息
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产品名称5-Aminovaleric acid
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述5-氨基戊酸(或5-氨基戊酸)是赖氨酸降解产物。它可以内源产生,也可以通过赖氨酸的细菌分解代谢产生。
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产品描述5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction: L-lysine leads to cadverine leads to L-piperideine leads 5-aminovalerate . In other words it is a metabolite of cadaverine which is formed via the intermediate 1-piperideine. Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue. High levels of 5-aminovalerate in biofluids may indicate bacterial overgrowth or endogenous tissue necrosis. In most cases endogenous 5-aminovalerate is thought to be primarily a microbial metabolite produced by the gut or oral microflora although it can be produced endogenously. 5-aminopentanoic acid is an in vivo substrate of 4-aminobutyrate:2-oxoglutarate aminotransferase .
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体外实验5-Aminovaleric acid is a normal metabolite present in human saliva, with a tendency to elevated concentration in patients with chronic periodontitis. 5-Aminovaleric acid is also believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist.It is also known as an antifibrinolytic amino acid analog and so it functions as a weak inhibitor of the blood clotting pathway.
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体内实验——
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同义词——
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通路Proteasome/Ubiquitin
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靶点Endogenous Metabolite
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受体others
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研究领域——
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适应症——
化学信息
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CAS Number660-88-8
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分子量117.15
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分子式C5H11NO2
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESNCCCCC(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Santos A Zanetta S Cresteil T et al. Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans[J]. Clinical Cancer Research 2000 6(5):2012-2020.
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